Students, perhaps you are aware about many recent reports that indicate
poor reproducibility of studies in biological sciences such as medicine.
Some estimate that about 50% (or more) of published studies are
unreproducible. While similar concerns have been expressed about
reproducibility of studies involving computations (e.g., in
computational biology) as far as I know there have been no studies
documenting how reproducible studies, involving numerical solutions of
ODE-based mathematical models, are. In the new course that I will be
teaching in Spring 2017 (Math 411) we will learn basics of mathematical
modeling (using examples from biology), learn basics of programming
(using open source software R), and perform analysis of published
mathematical models (both selected by me and students). The course will
be hands-on with mostly computer labs and will provide so-called
"experiential learning" for the students.
My hope is that by analyzing a number of representative papers we will
be able to write a report indicating reproducibility of ODE-based
mathematical models in biological (biomedical) literature. If results
are solid (e.g., we analyze a good number of papers), we will try to
publish these results as an article.
If you find this idea interesting, please register for the course. Let
me know if you have any questions.
Vitaly Ganusov
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Vitaly V. Ganusov
Associate Professor
M409 Walters Life Sciences
Department of Microbiology
Department of Mathematics
University of Tennessee
Knoxville, TN 37996-0845
USA
Phone: +1 865 974-4547
FAX: +1 865 974-4007
http://ganusovlab.utk.edu
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