Colleagues,
many of you know that billions of microorganisms live peacefully in our
guts but once in while some of these microbes can cause disease.
Following antibiotic treatment (e.g., after sore throat infection),
there are perturbations of composition of intestinal microbes
(microbiota) and in some individuals a specific type of bacteria, C.
difficile starts replicating causing severe diarrhea. I have started a
collaboration with a group which provided me with experimental data on
C.diff growth in intestines of mice which had been previously treated
with antibiotics. I am interested in recruiting an undergraduate student
with interest in biology to develop mathematical models for the analysis
of these data. In particular, I am interested in estimating how quickly
these bacteria multiply in the intestine and spread through intestine,
how quickly they form spores and what factors regulate production of the
toxin, the primary reason for diarrhea. Please email me if you are
interested in this project,
Vitaly Ganusov
--
Vitaly V. Ganusov
Assistant Professor
M409 Walters Life Sciences
Department of Microbiology
Department of Mathematics
University of Tennessee
Knoxville, TN 37996-0845
USA
Phone: +1 865 974-4547
FAX: +1 865 974-4007
http://web.bio.utk.edu/ganusov/
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